Skin tag removal bands work by cutting off blood supply to the skin tag, causing it to dry out, shrink, and eventually fall off over several days. They may be safe for small, clearly identified skin tags, but using them at home can carry risks such as pain, irritation, bleeding, infection, scarring, or treating the wrong type of skin growth, especially if the lesion is not actually a skin tag. You should avoid home removal and see a dermatologist if the skin tag is large, painful, bleeding, rapidly changing, located near the eyes/genitals, or if you are unsure of the diagnosis, since professional removal is safer and helps rule out other skin conditions.