Infliximab: Definition, Uses, and Clinical Overview

Infliximab is a biologic medication that targets tumor necrosis factor alpha (TNF-α), a key signal in inflammation. It is given most commonly by intravenous (IV) infusion in supervised clinical settings. In gastroenterology, it is widely used to treat inflammatory bowel disease (IBD), including Crohn’s disease and ulcerative colitis. It is also used in several non-gastrointestinal immune-mediated inflammatory diseases.

Azathioprine: Definition, Uses, and Clinical Overview

Azathioprine is an immunosuppressant medication that reduces overactive immune responses. It is commonly used as a long-term “maintenance” therapy in immune-mediated diseases. In gastroenterology, it is most often discussed in inflammatory bowel disease and autoimmune liver conditions. It is taken by mouth and typically works gradually rather than immediately.

Mesalamine: Definition, Uses, and Clinical Overview

Mesalamine is an anti-inflammatory medication used in inflammatory bowel disease (IBD). It is also called 5-aminosalicylic acid (5-ASA). It is most commonly used to treat ulcerative colitis, especially mild to moderate disease. It comes in oral and rectal formulations designed to deliver medication to the intestinal lining.

Rifaximin: Definition, Uses, and Clinical Overview

Rifaximin is a rifamycin-derived antibiotic that acts primarily inside the gastrointestinal (GI) tract. It is minimally absorbed into the bloodstream, so most of its activity is “luminal” (within the gut lumen). Clinicians most often use it in hepatology and gastroenterology for specific bowel- and liver-related conditions. It is prescribed as an oral medication rather than given by injection.

Prokinetics: Definition, Uses, and Clinical Overview

Prokinetics are medications that increase or coordinate movement (motility) in parts of the gastrointestinal (GI) tract. They are used when food, liquid, or gas moves too slowly or in an uncoordinated way. They are commonly discussed in disorders of the esophagus, stomach, and intestines. In clinical practice, they are part of symptom-based care for nausea, reflux-related symptoms, and constipation in selected cases.

Antacid: Definition, Uses, and Clinical Overview

An Antacid is a medication that neutralizes stomach acid in the upper gastrointestinal (GI) tract. It is commonly used for short-term relief of heartburn, acid indigestion, and dyspepsia (upper abdominal discomfort). Many Antacid products are available over the counter, and some are used in inpatient settings as supportive therapy.